The only 'trans' I oppose is a certain orange person's strange and distorted concept of 'transaction', but staying ON TOPIC, I see no harm in certain forms of genetic manipulation, and recognise the benefits in some instances. Having modified wheat to increase yield has saved millions from starving. It comes down to what end the science has in mind, and to what uses discoveries are put. If dire wolves are going to be bred to sell only to the wealthy as vanity symbols, then I begin to ask ethical questions. Benefit to the many must always outweigh status for the few.